Left-Right Patterning of the Heart

Grant number: DP180103159 | Funding period: 2018 - 2021

Completed

Abstract

This project aims to investigate how the heart responds to left-right (LR) signals, which tissue is dominant in this response; determine tissue intrinsic factors at play, and determine whether we can manipulate this. Expected outcomes include fundamental information about how organs are patterned.

Related publications (2)

Getting to the heart of left–right asymmetry: Contributions from the zebrafish model

KA Smith, V Uribe

2021-06-01

The heart is laterally asymmetric. Not only is it positioned on the left side of the body but the organ itself is asymmetric. This..

Talkin’ ‘bout regeneration: new advances in cardiac regeneration using the zebrafish

KA Smith, MT Mommersteeg

2020-04-01

The adult human heart has a very poor capacity to repair itself following injury. During heart attack, an enormous amount of cardi..

University of Melbourne Researchers

Kelly Smith